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J Exp Ther Oncol 8:327339 Sarafraz-Yazdi E, Mumin S, Cheung D, Fridman D, Lin B, Wong L, Rosal R, Rudolph R, Frenkel M et al (2022) PNC-27, a chimeric p53-penetratin peptide binds to HDM-2 in a p53 peptide-like structure, induces selective membrane-pore formation and leads to cancer cell lysis

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Jan 2001;37(1):79-83

While the exact etiology of AD remains unclear, its development is linked to a range of factors, including genetic predisposition, abnormal protein aggregation, neurotransmitter imbalance and neuronal damage (46)

This short exposure profile is consistent with its once-daily subcutaneous dosing in the clinical program